CICERO is a comprehensive online solution for the review of human, animal, and in vitro research. It is a cooperative effort among multiple committees responsible for supporting the research community at the University of Maryland. CICERO is where research teams can create and submit online all the forms needed for evaluation and approval of research studies by the Institutional Review Board (IRB), the Institutional Animal Care and Use Committee (IACUC), the Institutional Biosafety Committee (IBC), the Radiation Safety Committee (RSC), and the General Clinical Research Center (GCRC).